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STATs find that hanging together can be stimulating

Article Abstract:

Xiang Xu et al are studying how only 6 types of signal transducers and activators of transcription (STATs) transmit specific transcription commands to cell nuclei from a wide variety of cytokines and growth factors. The secret involves the method of binding of STAT dimers to GAS sequences.

Author: Leung, Stewart, Li, Xiaoxia, Stark, George B.
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1996
Genetic regulation, Genetic transcription, Transcription (Genetics)

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Catalysis by a multiprotein IkB kinase complex

Article Abstract:

Researchers recently identified a high molecular mass IkB kinase complex and two unusual IkB kinases. The findings have helped to answer some questions about the integration of multiple NF-kB signaling pathways, although some issues remained unresolved.

Author: Maniatis, Tom
Publisher: American Association for the Advancement of Science
Publication Name: Science
Subject: Science and technology
ISSN: 0036-8075
Year: 1997
Proteins

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Subjects list: Research, Cellular signal transduction
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