Antiaging medicine and mild cognitive impairment: practice and policy issues for geriatrics

Article Abstract:

The normal aging process results in mild cognitive impairment (MCI), which is also an intermediate stage between normal cognitive abilities and Alzheimer's disease. As the focus on antiaging medicines increases, the treatment of MCI becomes crucial. The economic, political, philosophic and practical implications of antiaging medicines for MCI are discussed. Suggestions are also offered to geriatricians regarding usage of such medicines for improving patient care.

United States, Aging, Cognition disorders, Cognitive disorders, Aging (Biology)

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Emerging antidementia drugs: a preliminary ethical view

Article Abstract:

The use of donepezil (Aricept) in the treatment of mild to moderate Alzheimer's disease raises many ethical questions. Many patients taking the drug temporarily recover memory and the ability to talk. This may please their caregivers but it may also make the patient aware of his or her condition, which could be very distressing. Those who had accepted their condition may become agitated or hard to manage again, which could place a burden on their caregivers.

Health aspects, Ethical aspects, Dementia, Aricept (Medication)

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Alprazolam as an alternative to low-dose haloperidol in older, cognitively impaired nursing facility patients

Article Abstract:

Alprazolam may be as effective as low-dose haloperidol in the treatment of agitation and disruptive behavior in cognitively impaired nursing home patients. Researchers compared the drugs in the treatment of 48 elderly patients, and found both were similarly effective. Alprazolam can produce less sedation, hypotension, movement disorders, memory problems, and other side effects associated with prolonged use of neuroleptic drugs like haloperidol.

Evaluation, Complications and side effects, Haloperidol, Alprazolam, Organic mental disorder, Organic mental disorders

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