What should the federal government do about Alzheimer's disease? Report of the Secretary's Advisory Panel on Alzheimer's disease

Article Abstract:

The Advisory Panel on Alzheimer's disease was established in 1987 to help to identify priorities and emerging issues with respect not only to Alzheimer's, but related dementias as well. That panel recently made recommendations that there be an increased budget (to $300 million per year) to fund at least half of approved grants and support 15 instead of the current 12 Alzheimer's research centers. It also recommended that 10 percent of the monies be allocated to specific types of study, and that federal monies be used to build facilities to house research activities. The panel also documents that the long-term care programs are inadequate and underfunded, and asks for long-term care legislation as a priority for Congress. While it is difficult to challenge the recommendations of the panel, it is not hard to question how such recommendations would affect research into other disorders, which would suffer. Also of concern is how the panel report will affect Congress and federal agencies, considering that cuts are proposed in catastrophic health insurance and that nursing homes are limiting the percentages of dementia patients they will accept. The recommendations, especially regarding long-term care, need the support of advocacy groups and information that will direct politicians away from the trend toward less comprehensive care. (Consumer Summary produced by Reliance Medical Information, Inc.)

Care and treatment, Social policy, United States. Department of Health and Human Services, editorial

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Self-recognition in Alzheimer's disease: a mirror and video study

Article Abstract:

The existence of self-recognition in 29 subjects with varying degrees of Senile Dementia of the Alzheimer Type (SDAT) was studied using mirror and video techniques. The 13 subjects with moderately severe cognitive decline had mirror self-recognition while 25% of those with severe cognitive decline did not show self-recognition in the mirror test. On the other hand, only seven showed self-recognition in the video test. The disappearance of video recognition ahead of the mirror self-recognition supports the regression hypothesis of Alzheimer's disease, which states that disappearance of psychological functions is the inverse of their appearance during ontogeny.

Regression (Psychology)

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Uptake of serotonin into platelets of senile dementia of the Alzheimer type patients

Article Abstract:

The serotonin uptake of platelets in patients with Alzheimer's disease was compared with age-matched normal elderly controls and young subjects. Results showed that there was lowerserotonin uptake in the platelets of Alzheimer's patients than in the elderly control and young subjects. The differences were due to decreased Vmax and not in the Km. Moreover, the change in not due to aberrations in the plasma.

Blood platelets, Serotonin metabolism

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