A switch between two modes of synaptic transmission mediated by presynaptic inhibition

Article Abstract:

Lateral gastric (LG) neuron-mediated modulatory commissural neuron 1 (MCN1) inhibition decreases the stimulation from MCN1 without affecting the excitatory effects. This switches the MCN1-excited network neurons. Electrotonic excitation from MCN1 to LG regulates LG neuron activity. The crustacean stomatogastric nervous system was used to analyze the MCN1 mechanism involved in stimulating the gastric mill rhythm.

Neural transmission, Neural transmission regulation

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Peripheral nerve injury triggers noradrenergic sprouting within dorsal root ganglia

Article Abstract:

An experiment conducted with rats revealed that noradrinergic axons sprout around the dorsal root ganglia as a result of peripheral nerve injury. These axons developed unique connections with nearby sensory neurons, an event which could account for the discharge observed after nerve damage. This form of contralateral sprouting is unique because the axons chose to target axotomized neurons.

Noradrenaline, Norepinephrine, Peripheral nerve diseases, Peripheral nervous system diseases

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