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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

DNA sequences and analysis of human chromosome 18

Article Abstract:

The finished sequence and gene annotation of human chromosome 18, which will allow a better understanding of the normal and disease biology of the chromosome, is reported. Despite the low density of protein-coding genes on chromosome 18, it is found that the proportion of non-protein-coding sequences evolutionarily conserved among mammals is close to he genome-wide average.

Author: Anderson, Scott, Kamal, Michael, Noguchi, Hideki, Engels, Reinhard, Butler, Jonathan, Xiaoping Yang, Itoh, Takehiko, Nusbaum, Chad, Whittaker, Charles A., Gnirke, Andreas, Jaffe, David B., Mauceli, Evan, Zody, Micahel C., Chang, Jean L., Abouelleil, Amr, Cook, April, Hafez, Nabil;C, Mikkelson, Tarjei S., O'Leary, Sinead B., Borowsky, Mark L., Cuomo, Christina A., Allen, Nicole R., Hall, Jennifer L., Lehoczky, Jessica, Naylor, Jerome W., Piqani, Bruno, Dewar, Ken, Norman, Catherine Hosage, Lui, Annie, Nicol, Robert, Kodira, Chinappa D., Taylor, Todd D., FitzGerald, Michael G., Bloom, Tony, Bugalter, Boris, Garber, Manuel, Macdonals, Pendexter, Nguyen, Cindy
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Nucleotide sequence, Base sequence, Human chromosomes

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The cell-cycle regulator geminin inhibits Hox function through direct and polycomb-mediated interactions

Article Abstract:

The clustered genes of the Hox family of homeobox proteins play an important role in embryonic development and proliferation. It is found that murine geminin associates transiently with members of the Hox-repressing polycomb complex, with the chromatin of Hox regulatory DNA elements and with Hox proteins.

Author: Kessel, Michael, Lingfei Luo, Xiaoping Yang, Yoshihiro Takihara, Knoetgen Hendrik
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004

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Reproduction in clusters

Article Abstract:

Homeobox genes consist of a characteristic DNA sequence and are essential for the numerous aspects of embryonic development. The clustering of the homeobox genes help in determining their spatial and temporal regulation and also, details of the 12 reproductive homeobox X-linked (Rhox) genes are given.

Author: Duboule, Denis, Spitz, Francois
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005

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Subjects list: Research, United States, Homeobox genes, Human cloning
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