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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

Article Abstract:

Mice are studied with reference to their overexpressing of a human uncoupling protein-3 (UCP-3). The results using magnetic resonance imaging show that these mice are hyperphagic and lean and that UCP-3 can affect metabolic rate.

Author: Clapham, John C., Arch, Jonathan R.S., Chapman, Helen, Haynes, Andrea, Lister, Carolyn, Moore, Gary B.T., Piercy, Valerie, Carter, Sabrina A., Lehner, Ines, Smith, Stephen A., Beeley, Lee J., Godden, Robert J., Herrity, Nicole, Skehel, Mark, Changani, K. Kumar, Hockings, Paul D., Reid, David G., Squires, Sarah M., Hatcher, Jonathan, Trail, Brenda, Latcham, Judy, Rastan, Sohaila, Harper, Alexander J., Cadenas, Susana, Buckingham, Julie A., Brand, Martin D., Abuin, Alejandro
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Mice, Mice (Rodents), Metabolic regulation

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Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice

Article Abstract:

Research is presented concerning the influence of lysosome-associated membrane protein-2 deficiency on the mortality of mice. The formation of vacuoles in key organs and tissues is discussed.

Author: Tanaka, Yoshitaka, Guhde, Gundula, Suter, Anke, Eskelinen, Eeva-Liisa, Hartmann, Dieter, Lullmann-Rauch, Renate, Janssen, Paul M.L., Blanz, Judith, von Figura, Kurt, Saftig, Paul
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Abnormalities, Lysosomes, Muscle cells

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Subjects list: Research, Proteins, Letter to the Editor
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