Genetics underlying inbreeding depression in Mimulus with contrasting mating systems

Article Abstract:

The genetic basis of inbreeding depression has mainly been examined in crop plants, where there is evidence for both overdominance-based and dominance-based depression. However, there is little information about the importance of such depressions in natural plant populations. A new study investigates the genetics underlying inbreeding depression in Mimulus with different mating systems. It is concluded that deleterious recessive alleles may cause inbreeding depression.

Genetic aspects, Plants, Heterosis, Inbreeding, Plant evolution, Scrophulariaceae

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Cognitive cartography

Article Abstract:

The cognitive maps required for spatial memory in rats placed in a box are regulated by place cells in the hippocampal region by a combination of distances from the walls of the box. The information is obtained by contact with the walls rather than by vision. Expanding the area of the box causes stretching and splitting of the place fields. The walls of the box contribute to the place cells and when their contribution increases beyond a certain point, the cells fire.

Geographical perception, Rats as laboratory animals, Laboratory rats

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Role of intercellular interactions in heterosynaptic long-term depression

Article Abstract:

The expression of heterosynaptic long-term depression (LTD) in the CA1 region of the hippocampus requires interactions between neurons. Different cell populations constitute the site of induction and expression of LTD. Spreading of the signal between the induction and expression neurons leads to the spread of heterosynaptic LTD. The heterosynaptic LTD is independent of a rise in postsynaptic calcium ions.

Depression, Mental, Depression (Mood disorder)

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