Glutamate-receptor genes in plants

Article Abstract:

Ionotropic glutamate receptors (GluRs) act as glutamate-activated ion channels in quick synaptic transmission. Genes encoding putative ionotropic GluRs are now known to exists in plants, and evidence is provided for their involvement in the transduction of light signals. Two full length complementary DNAs GLr1 and GLR2 were isolated from Arabidopsis and the membrane topology is analogous to animal ionotropic GLuRs. Arabidopsis GLRs also have similar sequence identity with animal aniotropic GLuRs in the GlnH1 signature domains.

Arabidopsis

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Prostaglandins stimulate calcium-dependent glutamate release in astrocytes

Article Abstract:

Astrocytes in the brain form a link with neurons, responding to neuronal activity, and synaptically releasing glutamate. It is shown that coactivation of the AMPA/kainate and metabotropic glutamate receptors (mGluRs) on astrocytes, leads cells to release glutamate via a Ca(super2+)-dependent method mediate by prostaglandins. Glutamate release is prevented by pharmacological inhibition of prostaglandin synthesis.

Observations, Prostaglandins, Astrocytes, Prostaglandin synthesis

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