Heartfelt enlightenment
Article Abstract:
It is possible for the circadian oscillators in zebrafish hearts and kidneys to be synchronized by light without any input from the eyes. This research involved monitoring Clock gene expression in heart and kidney organ cultures kept in reversed light-dark cycles. Two days following the reversal of the light-dark regimen, the phase of the Clock messenger RNA cycle had been offset by 12 hours, indicating that heart and kidney clocks could be entrained by light. It may now be possible to test whether cryptochromes are valid candidates as the photoreceptors used to entrain peripheral zebrafish clocks.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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New cogwheels in the clockworks
Article Abstract:
The nature of the clock genes that control daily fluctuations in an organism's behaviour and physiology is ill understood. Four new studies investigate the circadian oscillator and show how genes may make the clock tick in mammals and flies. It is shown that the circadian clock comprises an input pathway, a central pacemaker and an output pathway.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
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The ELF3 zeitnehmer regulates light signalling to the circadian clock
Article Abstract:
The circadian rhythm regulates biological and seasonal rhythms, including flowering. New research shows the circadian rhythm of early flowering 3 mutants of Arabidopsis thaliana, a long-day flowering plant that measures day length with a rhythm that is not reset during darkness.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
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