Left-right asymmetric expression of the TGF-beta-family member lefty in mouse embryos

Article Abstract:

Lefty, a gene of the transforming growth factor-beta family, is expressed asymmetrically in the left half of the gastrulating mouse embryo. The expression of lefty, which encodes a morphogen for left-right determination, is transient and occurs before the appearance of lateral asymmetry. Lefty is expressed in the lateral and the ventral midline in embryos having lesser number of somites. The sites of lefty expression are inverted in mouse mutants iv and inv, revealing that lefty is expressed downstream of iv and inv.

Genetic aspects, Mice, Mice (Rodents), Symmetry (Biology)

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A plant cyclin-dependent kinase inhibitor gene

Article Abstract:

A cyclin-dependent kinase (CDK) inhibitor, named ICK1, has been identified in Arabidopsis thaliana, using the yeast two-hybrid system. CDK inhibitors are important regulators of cell cycle and development. ICK1 has a unique structure, although it shares some similarities with the mammalian protein p27Kip1. The new CDK inhibitor is the first to be isolated from a plant and may be of use in studying the role of plant CDK inhibitors.

Observations, Genetic recombination, Arabidopsis thaliana, Cell research, Cytological research

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Control of root growth and development by cyclin expression

Article Abstract:

Cyclin expression limits indeterminate growth in the regulatory hierarchy of Arabidopsis plants, indicating that cyclin abundance allows plant growth to react to changes in the environment. The ectopic expression of cdc2 and cyc genes were studied to see the impact of expression on root growth.

Growth, Roots (Botany)

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