Marsupial Y chromosome encodes a homologue of the mouse Y-linked candidate spermatogenesis gene Ube1y
Article Abstract:
The discovery of a functional marsupial Y-linked homologue gene of the murine Ube1y gene proves that the Metatherian (marsupial) and Eutherian (placental) infraclasses of the mammalian subclass Theria evolved from a single ancestor, probably between 120 and 150 million years before present. This Ube1y gene contributes to the development of males among both marsupials and placentals by triggering spermatogenesis. This finding confirms the molecular and genetic link between marsupials and placentals.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1992
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Arrest of spermatogenesis and defective breast development in mice lacking A-myb
Article Abstract:
The role of A-myb in spermatogenesis and mammary gland development was established by utilizing genomic fragments cloned from a-myb homozygous mice. Results revealed that a-myb gene spliced mice develop to full term but exhibited defects in growth and male infertility due to arrested spermeiogenesis at the pachytene phase. Female adult a-myb gene spliced mice show underdeveloped lactating breast tissues.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1997
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In the platypus a meiotic chain of ten sex chromosomes shares genes with the bird Z and mammal X chromosomes
Article Abstract:
The behavior of platypus sex chromosomes and the theories on the evolution of sex determination is studied. The study demonstrates that platypus has fine male specific chromosomes (Y chromosomes) and five chromosomes present in one copy in males and two copies in female Cx chromosomes.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
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