Reversing the kinesin ratchet - a diverting tail

Article Abstract:

Kinesins are motor proteins moving along microtubules in just one direction. However an experiment by Henningsen and Schliwa has forced kinesins to reverse their usual direction by splicing them to the tail of Neurospora kinesin (Nkin), a plus-end kinesin. The experiment gives an insight into the stepping action by which the motor progresses along the microtubule.

Research & Development, Scientific Research and Development Services, Research institutes, Physiological aspects, Proteins

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Kinesin steps back

Article Abstract:

Kinesin molecular motors are the nanometrescale machines that are the major agents of large-scale self-organization inside cells. Kinesins are shown to move along microtubules by a walking mechanism by the study which uses improved optical trapping techniques.

Science & research, Microtubules, Optical properties, Optical tomography

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