NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury
Article Abstract:
N-methyl-D-aspartate (NMDA) receptor subunit expression on oligodendrocyte processes, and the presence of NMDA receptor subunit messenger RNA in isolated white manner is presented. The NMDA receptors bestow a high sensitivity to acute injury and represent an important new target for drug development in a variety of brain disorders.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
NMDA receptors are expressed in oligodendrocytes and activated in ischaemia
Article Abstract:
Simulating ischaemia led to the development of an inward current in oligodendrocytes, which is partly mediated by NMDA receptors. These results point to NMDA receptors of unusual submit composition as a potential therapeutic target for preventing white matter damage in a variety of diseases.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
User Contributions:
Comment about this article or add new information about this topic:
Feeding the brain
Article Abstract:
The blood flow is increased in the active areas of the brain to provide more energy to nerve cells. The brain's information-processing capacity is limited by the amount of energy available and so blood flow is increased to brain areas where nerve cells are active.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: The record for marine isotopic stage 11. Constraints on hydrothermal processes and water exchange in Lake Vostok from helium isotopes
- Abstracts: Planar cell polarity signaling couples cell division and morphogenesis during neurulation. Regulation of lethal giant larvae by Dishevelled
- Abstracts: A volcanic environment for bedrock diagenesis at meridiani planum on Mars. Implications for hydrologic processes on Mars from extensive bedrock outcrops throughout Terra Meridiani
- Abstracts: Insights form the genome of the biotrophic fungal plant pathogen Ustilago maydis. Genome sequencing and analysis of Aspergillus oryzae