NMDA spikes in basal dendrites of cortical pyramidal neurons

Article Abstract:

Synaptic processing in basal dendrites can be analyzed by identifying fine dendritic branches using fluorescence confocal microscopy and mimicking excitatory postsynaptic potentials by ultraviolet laser glutamate uncaging. It was shown that coactivation of clustered neighbouring basal inputs initiated local dendritic spikes which were accompanied by large calcium transients limited to the activated dendritic segment. N-methyl-D-aspartate spikes could make a unique contribution to synaptic processing.

Neural transmission, Synaptic transmission, Methyl aspartate, N-methyl-D-aspartate

---

K+ channel regulation of signal propagation in dendrites of hippocampal pyramidal neurones

Article Abstract:

Mammalian neurons have branches of dendrites that receive and integrate sensory signals but, until now, it has been unclear how such inputs are processed. Researchers have found potassium channels in dendrites from hippocampal pyramid neurons. The presence of such channels could explain some questions about dendritic function. The A-type channels could act to counter dendritic polarization.

---

Dendritic shock absorbers

Article Abstract:

Research shows that dendrites of hippocampal pyramidal neurons have potassium channels, which play an important part in dendrite excitability. It is proposed that dendritic A-type potassium channels could control dendritic spiking, leading to a greater inflow of calcium into the dendritic spines, regulated by different parts of the dendritic tree.

Similar abstracts:

• Abstracts: Microbes reveal extent of biodiversity. Botanical identities. Excessive fat intake can throw out the body clock
• Abstracts: Abnormal temporal dynamics of visual attention in spatial neglect patients. A vision over time and space
• Abstracts: Museum studies measure FA. Experimental design and the signalling properties of fluctuating asymmetry. The biological relevance of testing for perfect symmetry
• Abstracts: Congress and Varmus in clash over 'illegal' embryo research. High-level ethics committee 'needed to guide genetics policy.'

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.