Permutations of permeability

Article Abstract:

Ion channels acts as gatekeepers by allowing certain ions to pass across the membrane and excluding others, these proteins thereby controlling the electrical state of the cell. Channels selective for potassium ions allow K(super +) to exit the cell, causing hyper-polarization of the membrane and decreasing the cell's electrical excitability, but the basis for Na(super +) permeability is unclear, which is clarified by the revelation of the atomic structure of a channel, the NaK channel, with both K (super +) and Na (super +) permeability.

Potassium channels, Cells, Cell permeability, Atomic properties

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A paddle in oil

Article Abstract:

A study about the voltage-gated ion channels in cell membranes suggests that the correct lipid molecules in the membrane is essential if the ion channels are to open when the voltage changes across the membrane. The study results show that negatively charged phosphate groups are an essential component for correct paddle operation in membrane acting as counterions for the positively charged arginine amino-acid residues in the paddle, stabilizing the charged paddle in the lipid bilayer.

Physiological aspects, Cell membranes, Arginine

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Rotational movement during cyclic nucleotide-gated channel opening

Article Abstract:

Research is presented concerning the use of a histidine scan to investigate the influence of cyclic nucleotide-gated channels in signaling pathways connected with olfactory, visual and gustatory functions.

Letter to the Editor, Nucleotides, Visual pathways, Histidine, Olfactory nerve, Visual pathway

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