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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Regulation of Toll/IL-1-receptor-mediated gene expression by the inducible nuclear protein I(kappa)B(zeta)

Article Abstract:

Studies reveal that I(kappa)B(zeta) is indispensable for the expression of a subset of genes activated in Toll-like receptors (TLR)/Interleukin (IL)-1R signaling pathways where I(kappa)B(zeta)-deficient cells show severe impairment of IL-6 production. The fact that I(kappa)B(zeta) is an inducible protein, TLR/IL-1R mediated IL-6 expression may be regulated in a two-step mechanism.

Author: Kiyoshi Takeda, Masahiro Yamamoto, Soh Yamazaki, Shunsuke Yamamoto, Satoshi Uematsu, Shintaro Sato, Tatshushi Muta, Hiroaki Hemmi, Katsuaki Hoshino, Tsuneyasu Kaisho, Hirotaka Kuwata, Shizuo Akira, Osamu Takeuchi, Koichiro Takeshige, Tatsuya Saitoh, Shoji Yamaoka, Naoki Yamamoto
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Membrane proteins, Genes

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Regulated degradation of a class V myosin receptor directs movement of the yeast vacuole

Article Abstract:

Biochemists have discovered a mechanism in yeast cells that regulates the position of organelles within the cell. Analysis of this mechanism reveals a transport complex that can be assembled or disassembled to ensure the vacuole reaches the proper destination.

Author: Teng, Fusheng, Kauffman, Emily J., Novak, Jennifer L., Nau, Johnathan J., Catlett, Natalie L., Weisman, Lois S.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2003
Analysis, Physiological aspects, Yeast fungi, Yeasts (Fungi), Cytokinesis

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Mutation of F1G4 causes neurodegeneration in the pale tremor mouse and patients with CMT4J

Article Abstract:

The studies related to a multi-organ disorder with neuronal degeneration in the central nervous system identified pathogenic mutation of human F1G4 on chromosome 6q21 as hereditary motor and sensory neuropathy.

Author: Lupski, James R., Weisman, Lois S., Jun Li, Chow, Clement Y., Yanling Zhang, Dowling, James J., Jin, Natsuko, Adamska, Maja, Shiga, Kensuke, Szigeti, Kinga, Shy, Michael E., Xuebao Zhang, Meisler, Miriam H.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Health aspects, Nervous system, Central nervous system, Multiple organ failure, Neurodegenerative diseases

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Subjects list: Research, Cytology
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