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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Resourceful imprinting

Article Abstract:

Unequal genes of a child that are a copy from either the mother or the father, are turned off in some cases affecting the child's ability to acquire resources in the womb, after birth, and perhaps throughout life. The option to switch off one gene copy, termed as genomic imprinting, is through epigenetic mechanism of gene regulation in which the gene's sequence is unchanged but its labeling with certain chemical groups is altered.

Author: Reik, Wolf, Kelsey, Gavin, Constancia, Miguel
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
United States, Genetic research, Genomic imprinting

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The X-inactivation yo-yo

Article Abstract:

Mammals evolved a unique form of dosage compensation called X-chromosome inactivation in which one of the two X chromosomes in female cells is silenced by factors such as chemical modification of the DNA. However, during early development of female mouse embryos and in the placenta, the X chromosome derived from the father is always inactivated.

Author: Reik, Wolf, Ferguson-Smith, Anne C.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
United Kingdom, Sexual behavior, Analysis, Genetic aspects, DNA testing, DNA identification, X chromosome, Structure

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Stability and flexibility of epigenetic gene regulation in mammalian development

Article Abstract:

The interplay between transcription factors and epigenetic factors are used to describe the regulation of pluripotency and development. The analysis has shown that evolutionary epigenetics and epigenomic will have a vital role in discovering links between developmental adaptations and epigenetic regulators.

Author: Reik, Wolf
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2007
Genetic regulation, Epigenetic inheritance

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Subjects list: Research, Physiological aspects, Mammals
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