Silent glutamatergic synapses and nociception in mammalian spinal cord
Article Abstract:
Sensory information from the periphery of the spinal cord is conveyed by neurons in the superficial dorsal horn. Some synapses between spinal dorsal horn neurons and primary afferent fibres may be muted. A new study shows that silent synapses exist in some cells in the superficial dorsal horn and will not respond unless the holding potential is increased. It is suggested that silent synapses may be involved in persistent pain.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
How fast can you go?
Article Abstract:
As with other rhythmic motor behaviours, locomotion relies on a finely tuned neuronal network that is headquartered in the spinal cord and the ensemble of spinal neurons that generates a coordinated rhythmic activity known as a central pattern generator. The rhythm and periodicity of this network determines movement features such as the alternation between left and right, or the speed of walking, jumping or swimming.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin beta2
Article Abstract:
Characterization of mice with a targeted mutation of the s-laminin gene shows that the formation of motor nerve terminals is regulated by s-laminin, a homologue of the B1 chain of basal lamina glycoprotein, laminin. These s-laminin fragments selectively bind motor neuron-like cells and block neurite outgrowth mediated by other matrix molecules.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1995
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Effect of a supply of raw or rapeseeds on digestion in dairy cows. Use of oral tolerance tests to investigate disaccharide digestion in neonatal foals
- Abstracts: Helicase snaps back. Socialism in one country. Cuba-innovation through synergy
- Abstracts: Environmental trifluoroacetate. Variations in atmospheric methane concentration during the Holocene epoch. Warming debate highlights poor data
- Abstracts: Two shades beyond Neptune. And all was light. Light through a gravitational lens
- Abstracts: Good reception in fruitfly antennae. Splits in fruitfly Hox gene complexes. Memories of a fruitfly