Strategies for mitigating an influenza pandemic

Article Abstract:

A large-scale epidemic simulation model of pandemic influenza transmission is used to examine intervention options should initial containment of a novel influenza outbreak fail, using Great Britain and the United States as examples. Results reveal that household quarantine is potentially most effective social distance measure and that reactive school closure has little impact on overall attack rates.

United Kingdom, Government domestic functions, Health aspects, Control, Quarantine, Health policy

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Ecological and immunological determinants of influenza evolution

Article Abstract:

The ecological and immunological factors underlying the effects of influenza using a mathematical model is explored, capturing both realistic epidemiological dynamic and viral evolution at the sequence level. The data collected reveals that short-lived strain-transcending immunity is essential to restrict viral diversity in the host population.

Science & research, Research, Prevention, Risk factors, Immunization, Epidemics

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Dimensions of superspreading

Article Abstract:

Superspreading occurs in most of the diseases, however, its extent depends on the disease. The result shows that control efforts are aimed to identify the highly infectious superspreaders and use vaccinations to stop the spread of disease.

Usage, Causes of, Communicable diseases, Disease transmission, Vaccines

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