Structural basis for the promiscuous biosynthetic prenylation of aromatic natural products

Article Abstract:

The gene identification, biochemical characterization, and high-resolution x-ray crystal structures of an architecturally novel aromatic PTases is reported. The crystal structures, coupled with in vitro assays provide a basis for understanding and potentially manipulating the regio-specific prenylation of aromatic small molecules, using this structurally unique family of aromatic PTases.

United States, Analysis, Crystals, Crystal structure, Aromatic plants

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Self-incompatibility in Papaver targets soluble inorganic pyrophosphatases in pollen

Article Abstract:

The cytosolic phosphoprotein p26.1 comprises of two proteins, Pr-p26.1a and Pr-p26.1b that are soluble inorganic pyrophosphatases (sPPases) and it is shown that phosphorylation inhibits sPPase activity. The identification of sPPases as a target for the self-incompatibility (SI) signals in Papaver pollen has represented a significant advance in understanding SI.

United Kingdom, Field crops, except cash grains, not elsewhere classified, Oilseed (except Soybean) Farming, Poppyseed, Composition, Pyrophosphates, Poppies

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Self-incompatibility triggers programmed cell death in Papaver pollen

Article Abstract:

Data demonstrating that DNA fragmentation was inhibited by pretreatment with the caspase-3 inhibitor I peptide, Ac-DEVD-CHO (DEVD) is presented. The data reveals that the response is biphasic; rapid inhibition of pollen-tube growth is followed by programmed cell death (PCD), which is involved in a later edecision-making' phase, making inhibition irreversible.

Peptides

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