Structure of mitochondrial ADP/ATP carrier in complex with carboxyatractyloside

Article Abstract:

Crystal structure of the mitochondrial ADP/ATP carrier protein complexed with its inhibitor, carboxyatractyloside, reveals that it consisits of six alpha-helices from a compact transmembrane domain. The domain surface towards the space between inner and outer mitochondrial membrane exhibits a deep depression. Furthermore, it possesses an hexapeptide carrying the nucleotide RRRMMM at the bottom.

Carrier proteins, Transport proteins, Membrane proteins, Mitochondrial membranes, Mitochondrial membrane

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Framework for a molecular prison

Article Abstract:

Clathrates, a unique family of solid exists in which host compounds hold guest molecules captive in their rooms. A new atomic framework of cages for nitride clathrate is presented, the unprecedented topology of which, opens up new avenues for research.

Science & research, Research, Analysis, X-ray crystallography, Hydrogen bonding, Hydrogen bonds, Clathrate compounds, Catalysis, Chemical properties

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The whole tooth

Article Abstract:

Robert Macchiarelli, a professor of human palaeontology at the University of Poitiers, France, talks about his life as a palaeoanthropologist. His personal likes and dislikes are discussed.

Interview, Paleoanthropologists, Macchiarelli, Robert

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