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Zoology and wildlife conservation

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Abstracts » Zoology and wildlife conservation

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

Article Abstract:

The comparative analysis of the human, mouse, rat and dog genomes to create a systematic catalogue of common regulatory motifs in promoters and 3' untranslated regions (3' UTRs) are presented. MicroRNAs (miRNAs) regulate at least 20% of human genes and the overall result provides a systematic view of gene regulation in the human, which can be refined as additional mammalian genomes become available.

Author: Golub, Todd R., Lander, Eric S., Kellis, Manolis, Jun Lu, Lindblad-Toh, Kerstin, Xiaohui Xie, Kulbokas, E.J., Mootha, Vamsi
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2005
Analysis, Observations, RNA, Mammals, Genetic research, RNA synthesis

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Genomic analysis of metastasis reveals an essential role for RhoC

Article Abstract:

Research describing a genomic analysis of metastasis is presented. GTpase RhoC is found to enhance metastasis when overexpressed, but a dominant-negative Rho hinders metastasis.

Author: Clark, Edwin A., Golub, Todd R., Lander, Eric S., Hynes, Richard O.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2000
Cancer research, Cancer, Metastasis, Cancer metastasis

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Proof and evolutionary analysis of ancient genome duplication in the yeast Saccharomyces cerevisiae

Article Abstract:

The erosion of the yeast Saccharomyces cerevisiae is demonstrated. The ancestry of the yeast genome makes it possible to study the fate of duplicated genes.

Author: Lander, Eric S., Kellis, Manolis, Birren, Bruce W.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Food preparations, not elsewhere classified, All Other Miscellaneous Food Manufacturing, Brewers' Yeast, Brewer's yeast, Saccharomyces cerevisiae

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Subjects list: Research, Genetic aspects, Genomes
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