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Zoology and wildlife conservation

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The hyperthemophile chromosomal protein Sac7d sharply kinks DNA

Article Abstract:

Sac7D and SSo7D are proteins in a group of small chromosomal proteins from the hyperthermophilic archaeon Sulfolobus acidocaldarius and S. solfactaricus. They are extremely heat, acid and chemical agent stable, and Sac7d bins to DNA without particular sequence preferences, increasing melting temperature. The crystal structure of Sac7d in complex with two DNA sequences has been solved and refined. Kinking of the DNA helix is marked and results from the intercalation of specific hydrophobic side chains of Sac7d in the DNA structure.

Author: Robinson, Howard, Gao, Yi-Gui, McCrary, Bradford S., Edmonson, Stephen P., Shriver, John W., Wang, Andrew H.J.
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 1998
Proteins, DNA binding proteins

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From the top

Article Abstract:

The basic building blocks of matter are quarks and leptons, grouped in three generations and precise knowledge of the mass or the top quark and its interaction is key ingredient in testing theory against experimental data. The findings suggest that data from linear collider could improve the accuracy on the top quark mass.

Author: Weiglein, Georg
Publisher: Macmillan Publishing Ltd.
Publication Name: Nature
Subject: Zoology and wildlife conservation
ISSN: 0028-0836
Year: 2004
Science & research, Quarks, Leptons (Nuclear physics), Leptons

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