brinker is a target of Dpp in Drosophila that negatively regulates Dpp-dependent genes

Article Abstract:

Research into the molecular cloning of brinker (brk), a Decapentaplegic protein (Dpp) target that negatively regulates Dpp signalling, indicates that brk expression is repressed by dpp. brk encodes, a protein that negatively regulates Dpp-dependent genes. Brk was found to repress the transcriptional targets of Dpp in the Drosophila wing disc. Dpp activates transcriptional targets by repressing brk, a model that fits in with the presumed distribution of Dpp and the observed expression pattern of brk.

Cloning, Drosophila

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Negatively successful

Article Abstract:

One major problem with electronic devices based on organic materials is that they are only efficient at carrying electronic current via positive charge barriers, hence in order to realize a complete electronic circuit, devices must also carry negative charge for which a design principle is demonstrated. A guiding principle in the design of semiconductor and electrode materials for n-channel field-effective transistors (FETs) is to optimize energy levels so as to achieve high electron mobility.

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A negatively powered lens in the chameleon

Article Abstract:

Examination of the natural accommodation in the chameleon eye as functions of time and distance by a new technique reveals that accommodation is efficient to function as the major distance cue, and large retinal images are necessary for accurate focusing. Image magnification in chameleon's eye is higher than that in any other vertebrate eye of similar size. Negative refractive power of the crystalline lens of the chameleon is responsible for this efficient image magnification.

Eye, Ocular refraction, Chameleons

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