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Biology beyond the buzz: Lessons from EGFR research show how to kick-start a systems approach for other areas of biology

Article Abstract:

The study of the epidermal growth factor receptor (EGFR) will help to accurately describe and predict how signal transduction pathways function in both normal and diseased cells and once perfected it will change the way biological research is conducted. The EGFR system is thus a model for understanding basic receptor biochemistry and provides important lessons for the transition to systems biology as well, especially in research in the field of immunology and metabolism.

Author: Wiley, H. Steven
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2006
Biochemistry, Transduction, Transduction (Genetics), Epidermal growth factor receptors

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The network within

Article Abstract:

Ilya Shmulevich, an associate professor at the Institute for Systems Biology (ISB) in Seattle, is using creative computation for deciphering gene regulation. He uses his own novel computational models to map genetic networks, classify cancers, understand immune responses and has been greatly successful in this endeavor.

Author: Philips, Melissa Lee
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2006
Computer Scientists, Usage, Genetic regulation, Gene expression, Computational biology, Shmulevich, Ilya

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What if humans were designed to last?

Article Abstract:

Experts in gerontology, neuroscience, genetics, cell biology, development and health and fitness science have devised a human that would stand the test of time. They have tried to imagine the inner working of the human body and create innovative approaches tackling the problems of an aging body.

Author: Olshansky, S. Jay, Carnes, Bruce A., Butler, Robert N.
Publisher: Scientist Inc.
Publication Name: The Scientist
Subject: Biological sciences
ISSN: 0890-3670
Year: 2007
Cellular Biology, Cytology, Gerontology, Neurosciences

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Subjects list: Research, United States
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