Pathway to totipotency: Lessons from germ cells
Article Abstract:
The characteristics that distinguish germ cells from somatic cells and speculate on the mechanisms that allow germ cells to develop, proliferate, and differentiate while avoiding the loss of totipotency that befalls somatic cells is discussed. The remarkable plasticity and regenerative abilities of germ cells suggests that germ cells maintain a totipotent genome through most of development.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
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Molecular biology select
Article Abstract:
Small RNAs with likely functions in spermatogenesis and genome stability are present in the germlines of mammals and flies. A study is conducted in order to explain how to achieve tissue-specific expression of a small RNA, which is essential for cell integrity, regulating gene expression at the levels of translation, RNA degradation and chromatin.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 2006
User Contributions:
Comment about this article or add new information about this topic:
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