Cell fate decisions within the mouse organizer are governed by graded Nodal signals
Article Abstract:
Research has been conducted on cell fate decisions. Results demonstrate that these decisions are governed by graded Noda1/Smad2 signals, and that Smad2-dependent signals regulate the formation of PCP precursor populations and the definitive endoderm.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Central nervous system, Genetic research, Embryo
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
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Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
Article Abstract:
Research has been conducted on tuberous sclerosis complex-2. The authors demonstrate that this complex has GTPase-activating protein activity toward Rheb in vitro, and that tuberous sclerosis complex-2 regulates Rheb-GTP levels in vivo.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Causes of, Gene mutations, Gene mutation, Growth, Genetic regulation, Phosphorylation, Chemical inhibitors, Company growth, Tuberous sclerosis, Guanosine triphosphatase, GTPases
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
Comment about this article or add new information about this topic:
Subjects list: United States, Analysis, Physiological aspects, Genetic aspects, Cells (Biology), Proteins, Cells
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