Cream fur: a new mouse mutation that may cause unusual lipid metabolism
Article Abstract:
A cream yellow coat color had been found in a breeding colony of albino mouse of strain CAL20. Genetic studies showed that the cream yellow coat color phenotype was regulated by a single recessive mutant gene on chromosome 13. The cream yellow hair was also found to have more fatty acid than normal hair and that the color was due to an unusual lipid metabolism. The locus was named cream fur locus and was given the symbol crf. It was also observed that recombination frequencies near the area of the crf locus were very different between male and female meiosis.
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1998
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Interspecies approaches for the analysis of parental imprinting during mouse development
Article Abstract:
Genomic imprinting causes functional specialization of the parental genomes during development, resulting in offspring inheriting just one active copy of a gene. The molecular imprinting mechanism is not known but it is thought that the genome specialization is established during gametogonesis. An interspecies mRNA phenotyping method to detect allele-specific gene expression in mice and to identify candidate imprinted genes in mammals is described.
Publication Name: The Journal of Heredity
Subject: Biological sciences
ISSN: 0022-1503
Year: 1997
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