Evolution and development: Wnts in deep time

Article Abstract:

A report published in Nature, Kusserow and colleagues in 2005 reveals that the Wnt genes evolved much earlier than previously thought and played a crucial role in the diversification of metazoan body plans. The Wnt gene is a family of signaling proteins, which plays an important role in the critical intercellular signaling events in animal development and adult tissue homeostasis.

Author: Primus, A, Freeman, G
Genetic research, Homeotic genes

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Efficiency of triple test cross for detecting epistasis with marker information

Article Abstract:

The efficiency of the triple test cross (TTC) which is an experimental design for analyzing epistasis and estimating the components of genetic variance for quantitative traits was extended to include molecular information. The results demonstrate that the TTC may have increased power to detect epistasis when marker information is present.

Author: R. Zhang, C. Zhu
China, Analysis, Genetic epistasis, Epistasis, Quantitative trait loci, Genetic variation

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An indication of major genes affecting hip and elbow dysplasia in four Finnish dog populations

Article Abstract:

A Bayesian segregation analysis was performed on four dog populations to assess the existence of major genes influencing hip and elbow dysplasia. The results showed the existence of a major gene for hip dysplasia in all the breeds and for elbow dysplasia in one breed.

Author: Mak, K., Janss, L.L.G., Groen, A.F., Liinamo, A.E., Ojala, M.
United States, Genetic aspects, Dogs, Dysplasia

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Subjects list: Research, Animal genetics
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