Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Haplotype analysis for Icelandic families defines a minimal interval for the macular corneal dystrophy type I gene

Article Abstract:

Location of the gene for macular corneal dystrophy (MCD) type 1 has been narrowed to a region of less than 1 cM between markers D16S3115 and D16S3083 through a haplotype analysis of 10 Icelandic families. Evidence also suggests that the different immunophenotypes of MCD may be allelic. MCD type I in Iceland may have been caused by multiple mutations or else a very old mutation with multiple recombinants.

Author: Pericak-Vance, Margaret A., Baldwin, Jennifer, Stajich, Jeffrey M., Vance, Jeffery M., Liu, Ning-Pu, Jonasson, Fridbert, Dew-Knight, Susan, Lennon, Felicia, Klintworth, Gordon K.
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 1998
Iceland, Genetic disorders, Corneal diseases

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration

Article Abstract:

A study to identify statistically the most likely age-related macular degeneration (AMD) -susceptibility allele by using the Genotype-IBD sharing test and conditional haplotype analysis is presented. Genetic susceptibility coupled with a modifiable lifestyle factor such as cigarette smoking confers a significantly higher risk of AMD than either factor alone.

Author: Pericak-Vance, Margaret A., Haines, Jonathan L., Scott, William K., Hauser, Michael A., Schmidt, Silke, Gallins, Paul, Wong, Frank, Yu Sarah Chen, Spencer, Kylee, Schnetz-Boutaud, Nathalie, Postel, Eric A., Agarwal, Anita
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2006
Tennessee, Causes of, Risk factors, Smoking, Haplotypes, Macular degeneration

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Peakwide mapping on Chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease

Article Abstract:

A susceptibility locus for coronary artery disease (CAD) is mapped to chromosome 3q13-21 in a linkage study of early-onset CAD to examine the association between genotype and aortic atherosclerosis. The peakwide survey found evidence of associations from the kalirin (KALRN) gene, especially in patients with early-onset CAD.

Author: Granger, Christopher B., Pericak-Vance, Margaret A., Haines, Jonathan L., Kraus, William E., Hauser, Elizabeth R., Nelson, Sarah, Vance, Jeffrey M., Liyong Wang, Harris, Marco, II, Hale, A. Brent, Shah, Svati H., Haynes, Carol, Crosslin, David, Hones, Christopher J.H., Crossman, David, Seo, David, Gregory, Simon G., Goldschmidt-Clermont, Pascal J.
Publisher: University of Chicago Press
Publication Name: American Journal of Human Genetics
Subject: Biological sciences
ISSN: 0002-9297
Year: 2007
United States, Coronary heart disease, Chromosome mapping

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Genetic aspects
Similar abstracts:
  • Abstracts: Randomly amplified polymorphic DNA analysis of clinical and environmental isolates of Vibrio vulnificus and other Vibrio species
  • Abstracts: Pure and mixed genetic lines of Saccharomyces bayanus and Saccharomyces pastorianus and their contribution to the lager brewing strain genome
  • Abstracts: A discordant sibship test for disequilibrium and linkage: no need for parental data. Efficient study designs for test of genetic association using sibship data and unrelated cases and controls
  • Abstracts: Linkage analysis of human leukocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/-C region
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.