Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Malignant glioma: genetics and biology of a grave matter

Article Abstract:

In this review the biology of the malignant brain tumors and its bearing in the development of a specific and an effective therapy are discussed. Data on histopathologic and genetic lesions of the lower-grade as well as highly aggressive glioma, glioblastoma are presented.

Author: Louis, David N., DePinho, Ronald A., Maher, Elizabeth A., Furnari, Frank B., Bachoo, Robert M., Rowitch, David H., Cavenee, Webster K.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2001
United States, Cancer research, Cancer, Histology, Pathological, Pathological histology

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Malignant astrotyic glioma: genetics, biology, and paths to treatment

Article Abstract:

A review highlighting the mechanisms underlying the genetics, biology and clinical behavior of glioblastoma and the scientific advances to improve the clinical course of this lethal disease is presented.

Author: Louis, David N., DePinho, Ronald A., Chin, Lynda, Hahn, William C., Furnari, Frank B., Bachoo, Robert M., Cavenee, Webster K., Ligon, Keith L., Fenton, Tim, Mukasa, Akitake, Stommel, Jayne M., Stegh, Alexander, Brennan, Cameron;
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2007
Physiological aspects, Cell cycle, Cancer invasiveness, Immunohistochemistry

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

Article Abstract:

The article discusses the identification and the significant functions of a PTEN-regulated STAT3 brain tumor suppressor pathway. The STAT3 pathway is found to behave differently in people with different genetic backgrounds and hence can be easily used for the development of a treatment for glioblastoma.

Author: DePinho, Ronald A., Levy, David E., Bachoo, Robert M., Bonni, Azad, Konopka, Genevieve, Puram, Sidharth V., Chan, Jennifer A., Mingjian J. You
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2008
Genetic transcription, Transcription (Genetics), Phosphorylation, Glioblastoma multiforme, Brain tumours

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Research, Analysis, Genetic aspects, Gliomas, Brain tumors
Similar abstracts:
  • Abstracts: PCR-based identification of MAT-1 and MAT-2 in the Gibberella fujikuroi species complex. Simple sequence repeat markers distinguish among morphotypes of Sphaeropsis sapinea
  • Abstracts: Chk1 is an essential kinase that is regulated by Atr and required for the G(sub.2)/M DNA damage checkpoint
  • Abstracts: Essential role for caspase 8 in T-cell homeostasis and T-cell-mediated immunity. Tumorigenesis in mice carrying a truncating Brca1 mutation
  • Abstracts: TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm
  • Abstracts: A p-loop motif and two basic regions in the regulatory protein GvpD are important for the repression of gas vesicle formation in the archaeon Haloferax mediterranei
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.