Implicating the glutathione-gated potassium efflux system as a cause of electrophile-induced activated sludge deflocculation

Article Abstract:

A study demonstrates that the glutathione-gated K(super +) efflux (GGKE) of cytoplasmic K(super +) occurs in activated sludge communities in response to shock loads of industrially relevant electrophilic chemicals. The analysis shows that shock loads of electrophilic chemicals result in very high K(super +) concentrations within the activated sludge floc structure and these K(super +) levels are comparable to that which caused deflocculation by external KCl addition.

Microbiological research, Glutathione, Electrophiles

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Transcriptome analysis reveals that multidrug efflux genes are upregulated to protect Pseudomonas aeruginosa from pentachlorophenol stress

Article Abstract:

The transcriptome response of a common soil bacterium, Pseudomona aeruginosa is examined to the common environmental contaminant pentachlorophenol (PCP). It is observed that the upregulation of the efflux pumps protected the cells from the potentially toxic effects of PCP allowing the physiological whole-cell function to remain constant.

Pesticide and Other Agricultural Chemical Manufacturing, Agricultural chemicals, not elsewhere classified, Pentachlorophenol, Physiological aspects, Pseudomonas aeruginosa

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Improvement of NADPH-dependent bioconversion by transcriptome-based molecular breeding

Article Abstract:

The development of enhanced model system for NADPH-dependent bioconversion from glucose metabolism in Escherichia coli is described. Transcriptome data from a xylitol-producing recombinant Escherichia coli are used to increase its productivity.

Genetic aspects, Escherichia coli, Xylitol, Chemical properties, NADP (Coenzyme), Nicotinamide adenine dinucleotide phosphate

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