Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Interchromosomal transfer of epigenetic states in Ascobolus: transfer of DNA methylation is mechanistically related to homologous recombination

Article Abstract:

The interaction between methylation transfer and meiotic recombination is addressed by a statistical approach. Evidence of methylation transfer in conjunction with meiosis is provided by crosses between methylated and unmethylated strains of the corresponding b2 alleles. Both methylation transfer and gene conversion show the same 5'-to-3' polarity along the b2 gene. Transfer of methylation also accompanies the conversion of a mutated site in the recipient unmethylated b2 allele. Both reactions are hindered by ectopic positioning of two b2 alleles or by nucleotidic divergence.

Author: Colot, Vincent, Rossignol, Jean-Luc, Maloisel, Laurent
Publisher: Elsevier B.V.
Publication Name: Cell
Subject: Biological sciences
ISSN: 0092-8674
Year: 1996
Physiological aspects

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Isolation of the Ascobolus immersus spore color gene b2 and study in single cells of gene silencing by methylation induced premeiotically

Article Abstract:

The mechanism of an epigenetic process called methylation induced premeiotically (MIP) in Ascobolus immersus was investigated in cloned A. immersus spore color gene b2, a site of active meiotic recombination. Several DNA transformation procedures were performed to isolate the whole gene and to produce a null b2 allele. Application of MIP to a duplicate b2 confirmed gene silencing after meiosis in single cells. Results also support that MIP regulates b2 expression.

Author: Colot, Vincent, Rossignol, Jean-Luc
Publisher: Genetics Society of America
Publication Name: Genetics
Subject: Biological sciences
ISSN: 0016-6731
Year: 1995
Fungi, Genetic transformation

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Suppression of crossing-over by DNA methylation in Ascobolus

Article Abstract:

DNA methylation appears to disrupt the meiotic recombination of the Ascobolus immersus fungus. Genome integrity is preserved because of this suppression as it stops chromosome rearrangements. When b2 spore color gene was methylated the crossing-over between the two markets next to the gene was considerably reduced.

Author: Rossignol, Jean-Luc, Maloisel, Laurent
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1998
Influence, Crossing over (Genetics)

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Subjects list: Genetic aspects, Genetic recombination, Methylation, Meiosis, Research
Similar abstracts:
  • Abstracts: Premature truncation of a novel protein, RD3, exhibiting subnuclear localization is associated with retinal degeneration
  • Abstracts: Structure of the Y chromosomal Su(ste) locus in Drosophila melanogaster and evidence for localized recombination among repeats
  • Abstracts: Gene transfer of Alcaligenes eutrophus JMP134 plasmid pJP4 to indigenous soil recipients. Constitutive expression of the cloned phenol hydroxylase gene(s) from Alcaligenes eutrophus JMP134 and concomitant trichloroethylene oxidation
  • Abstracts: A 450 kb transgene displays properties of the mammalian X-inactivation center. X chromosome inactivation is mediated by Xist RNA stabilization
  • Abstracts: Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo. Magnitude of binocular vision controlled by Islet-2 repression of a genetic program that specifies laterality of retinal axon pathfinding
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2023 Advameg, Inc.