Light and development regulate the expression of the albino-3 gene in Neurospora crassa

Article Abstract:

The albino(al)-3 locus in Neurospora crassa encodes two distinct though overlapping transcripts, al-3(m) or mycelial and al-3(c) or conidial. The two transcripts respond to different regulatory stimuli that act on distinct promoter regions. Patterns of response to light, conidiation and circadian rhythm have been investigated. The al-3 gene contains codes for geranylageranyl pyrophosphate synthase, an enzyme associated with the biosynthesis of carotenoids. The al-3(m) transcript was transiently expressed in the mycelium after light induction. The al-3(c) mRNA appeared in conidiating cultures only and varied according to the circadian cycle.

Author: Macino, Giuseppe, Carattoli, Alessandra, Arpaia, Giuseppina
Genetic regulation, Photobiology, Neurospora

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DRhoGEF2 encodes a member of the Dbl family of oncogenes and controls cell shape changes during gastrulation in Drosophila

Article Abstract:

DRhoGEF2 has been identified as a gene that is crucial in controlling cell shape changes during gastrulation by encoding a putative guanine nucleotide exchange factor. Mesodermal and endodermal primordia are unable to invaginate without maternal DRhoGEF2 genes. The gene appears to act independent of other genes in the signalling pathway.

Author: Perrimon, Norbert, Hacker, Udo
Analysis, Genetic aspects, Drosophila, Gastrulation, Cell research, Cytological research

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Subjects list: Research
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