Maltose/maltodextrin system of Escherichia coli: Transport, metabolism, and regulation
Article Abstract:
The maltose system is involved in the uptake and efficient catabolism of alpha(1-4)-linked glucose polymers. Transcriptional control has been the main focus of maltose system studies, due to the interest in a positively controlled system. The MalT protein, which activates at all mal promoters, has provided a significant alternative view to the lac operon. A review of what is currently known about the maltose system of E. coli is provided, concentrating on maltodexrin transport, internalized sugar metabolism and mal gene transcriptional regulation.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 1998
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DNA gyrase, topoisomerase lV, and the 4-quinolones
Article Abstract:
Topoisomerase lV causes decatenation of chromosomes that are linked together, though gyrase was originally thought to do this. Topoisomerase is also a target for an antibacterial agent called 4-quinolones which was previously viewed as targeting gyrase alone. Cell death can occur, though DNA damage caused by quinolone can be repaired using recombination pathways. Host-parasite interactions can be better understood by examining the interaction between quinolones and topoisomerase.
Publication Name: Microbiology and Molecular Biology Reviews
Subject: Biological sciences
ISSN: 1092-2172
Year: 1997
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