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Zebrafish hairy/Enhancer of split protein links FGF signaling to cyclic gene expression in the periodic segmentation of somites

Article Abstract:

A study shows the evidence that a Hes6-related hairy/Enhancer of split-related gene, her13.2, links fibroblast growth factor (FGF) signaling to the Notch-regulated oscillation machinery in zebrafish. Expression of her13.2 is found to be induced by FGF-soaked beads and decreased by an FGF signaling inhibitor.

Author: Kondoh, Hisato, Kawamura, Akinori, Koshida, Sumito, Hijikata, Hiroko, Sakaguchi, Takuya, Takada, Shinji
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
Genetic aspects, Fibroblast growth factors, Zebra fish, Zebra fishes

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Variant histone H3.3 is deposited at sites of nucleosomal displacement throughout transcribed genes while active histone modifications show a promoter-proximal bias

Article Abstract:

The distribution of histone H3 and its variant H3.3 relative to chromatin structure and elongating polymerase is examined. It is observed that H3 and H3.3 displaces and is followed by selective deposition of H3.3 upon gene induction.

Author: Schubeler, Dirk, Wirbelauer, Christiane, Bell, Oliver
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2005
Polymerase chain reaction, Meiosis

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Subjects list: Research, Gene expression, Genetic research
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