Regulatory divergence modifies limb length between mammals
Article Abstract:
The variation within populations caused by the differences in DNA sequences regulating gene expression is examined. Findings reveal that mutations accumulated in pre-existing noncoding regulatory sequences within a population are responsible for variation in the evolution of morphological differences between species.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2008
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Ovca1 regulates cell proliferation, embryonic development, and tumorigenesis
Article Abstract:
Ovarian cancer 1 (Ovca1) is a tumor suppresser that acts as a positive regulator for cell cycle progression. Evolution of ovarian, breast and other tumor phenotypes attributed to the coordinated loss of OVCA1 and p53 on the human Chromosome 17.
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2004
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BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning
Article Abstract:
A study examines the role of bone morphogenetic protein receptor in the mesenchyme of a vertebrate limb.
Publication Name: Developmental Biology
Subject: Biological sciences
ISSN: 0012-1606
Year: 2006
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