Signaling by transmembrane proteins shifts gears

Article Abstract:

The NMR structure of the HAMP domain is described, providing valuable insights into how the conformational change caused by a signal interacting with the external receptor domain is transduced to modulate the enzymatic activity of the kinase. It is proposed that the rotation of the HAMP domain would also move downstream elements by 26 degrees Celsius to transduce the signal and affect enzymatic activity.

Structure, Phosphotransferases

---

RTP family members induce functional expression of mammalian odorant receptors

Article Abstract:

A study demonstrates that the transmembrane proteins RTP1 and RTP2 promote functional cell surface expression of odorant receptors (Ors) expressed in HEK293T cells. Genes encoding these proteins are expressed specifically in olfactory neurons, the proteins interact with OR proteins and enhance the OR responses to odorants.

Genetic research, Genetic code

---

How the ER stays in shape

Article Abstract:

Two membrane proteins, Rtn4A/NogoA and DP1/Yop1p, contribute to the generation of tubular morphology in the endoplasmic reticulum (ER). The overexpression of Rtn4A results in long processes in a cultured fibroblast-like cell line.

United States, Physiological aspects, Endoplasmic reticulum, Growth, Xenopus, Company growth

Similar abstracts:

• Abstracts: Targeting of TAK1 by the NF-kappaB protein relish regulates the JNK-mediated immune response in Drosophila. A novel motif governs APC-dependent degradation of Drosophila ORC1 in vivo
• Abstracts: Multiple docking sites on substrate proteins form a modular system that mediates recognition by ERK MAP kinase
• Abstracts: Membrane dynamics in endocytosis. Synaptic protein synthesis associated with memory is regulated by the RISC pathway in Drosophila
• Abstracts: SAPKs and transcription factors do the nucleocytoplasmic tango. The induction of sexual development and virulence in the smut fungus Ustilago maydis depends on Crk1, a novel MAPK protein
• Abstracts: Growth temperature dependence of channel size of major outer-membrane protein (OprF) in psychotrophic Pseudomonas fluorescens strains

This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.