Structure, expression, and hormonal control of genes from the mosquito, Aedes aegypti, which encode proteins similar to the vitelline membrane proteins of Drosophila melanogaster

Article Abstract:

Two classes of genomic clones coding for genes expressed after a blood meal in the mosquito, Aedes aegypti, were isolated. One of the clones hybridized to a 6.5 kb message that was shown to code for vitellogenin. The other clone, the 15a gene, hybridized to a 0.65 kb message, which was examined in the study. It was shown that the transcription of the 15a gene occurs in the follicle cells of the ovary under the control of 20-hydroxyecdysone. Moreover, analysis revealed that the two genomic clones encode related proteins that are similar to the vitelline membrane proteins of Drosophila melanogaster.

Author: Yonggu Lin, Hamblin, Martha T., Edwards, Marten J., Barillas-Mury, Carolina, Kanost, Michael R., Knipple, Douglas C., Wolfner, Mariana F., Hagedorn, Henry H.
Membrane proteins, Zona pellucida

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Comparative genome analysis of the yellow fever mosquito Aedes aegypti with Drosophila melanogaster and the malaria vector Anopheles gambiae

Article Abstract:

An in silico comparative genomics approach enabled researchers to identify putative orthologs to genetically mapped genes from different mosquito genome databases, the yellow fever mosquito Aedes aegypti in Drosophila melanogaster and the primary malaria vector, Anopheles gambiae. As these databases offer limited scope for gene determination, genome sequencing projects with other dipteran species is needed.

Author: Severson, D. W., deBruyan, B., Lovin, D. D., Brown, S. E., Knudson, D. L., Morlais, I.
United States, Science & research, Anopheles, Aedes albopictus

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Developmental control elements in the promoter of a Drosophila vitelline membrane gene

Article Abstract:

Dissection of the promoter region of VM26A1 (a clone of the Drosophila vitelline membrane gene) indicated the presence of control elements that can promote the expression of lacZ reporter gene. Results of the experiment also indicate that 597 bp of 5' flanking DNA results in a lacZ reporter gene with sex, tissue and stage details similar to that found in the endogenous VM26A1 gene.

Author: Jin, Jingmin, Petri, William H.
Promoters (Genetics), Membranes (Biology)

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Subjects list: Research, Gene expression, Drosophila, Aedes, Genetic aspects
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