The dawn of bilaterian animals: The case of acoelomorph flatworms

Article Abstract:

The origin of the bilaterian metazoans from radial ancestors is one of the biggest puzzles in human evolution and the only way to solve it is to identify the nature and main features of the last common ancestor of the bilateralness (LCB). The LCB is considered to be a complex organism bearing several features of modern bilaterians.

Research and Development in the Physical, Engineering, and Life Sciences, Molecular Biology, Platyhelminthes, Flatworms

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Serial analysis of gene expression (SAGE): Unraveling the bioinformatics tools

Article Abstract:

Serial analysis of gene expression (SAGE) is a powerful technique that can be used for global analysis of gene expression, main benefits being the digital output and the identification of novel genes. An outline of the method, various bioinformatics methods for data analysis and general applications of the method are reviewed.

Computational biology, Serial analysis of gene expression

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A new bone to pick: osteoblasts and the haematopoietic stem-cell niche

Article Abstract:

The two transgenic models, Bone Morphogenetic Protein Receptor 1A gene and active PTH/PTHrP receptor mutant leads to increase in trabecular osteoblasts and number of HSCs. Research shows that osteoblasts are major, defining component of the HSC niche within the bone marrow.

Hematopoietic stem cells, Osteoblasts, Bone morphogenetic proteins

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