Abstracts » Biological sciences

The meiotic behavior of an inversion in Caenorhabditis elegans

Article Abstract:

A crossover suppressor for the right end of linkage group I in Caenorhabditis elegans was isolated and characterized. Gene mapping showed that this suppressor is an inversion, designated hIn1(I), the first genetically proven one in C. elegans. Further characterization of hIn1(I) showed that its meiotic properties are similar to those observed in Drosophila, including crossover suppression and intrachromosomal effects. It was concluded that hIn1(I) and chromosome I are capable of homolog recognition and synapsis, but physical constraints inside the inversion loop limit chiasmata formation, leading to suppression of crossing over in the region.

Genetic recombination, Inversion (Genetics)

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Two types of sites required for meiotic chromosome pairing in Caenorhabditis elegans

Article Abstract:

Researchers used translocations and duplications to localize the Caenorhabditis elegans chromosome I homolog recognition region (HRR) to the result extremity. The other end of the chromosome I did not reveal any capacity for homologs to pair and recombine. Inadequacies in this area primarily suppressed recombination to the middle of the chromosome, HRR assisted recombination, but failed to influence the distribution of the crossover events, indicating that there will be multiple initiation regions for recombination when homolog recognition has been attained.

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Mutant rec-1 eliminates the meiotic pattern of crossing over in Caenorhabditis elegans

Article Abstract:

The meiotic pattern of exchange events in Caenorhabditis elegans was investigated by measuring the frequency of crossing over for several intervals across chromosome I in strains mutant for the rec-1 gene and in him-6 and him-14 mutants. Mutations in rec-1, him-6 and him-14 disrupted the distribution of exchanges, resulting to a reduction in crossing-over between homologues.

Meiosis, Crossing over (Genetics)

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