A conserved structural motif reveals the essential transcriptional repression function of Spen proteins and their role in developmental signaling
Article Abstract:
Research has been conducted on Spen proteins which regulate transcriptional effector expression in diverse signaling pathway. Results demonstrate that these proteins play important role in the transcriptional repression complex in both nuclear receptor and Notch signaling pathways.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
United Kingdom, Proteins, Genetic transcription, Transcription (Genetics)
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
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siRNAs can function as miRNAs
Article Abstract:
Research has been conducted on RNA interference and related phenomena. The authors demonstrate that in mammalian tissue culture short interfering RNA can repress targen mRNA expression.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
United States, Catalysis
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
User Contributions:
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Subjects list: Analysis, Physiological aspects, Genetic aspects, Genetic regulation, Gene expression, RNA, Genetic research
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