Abstracts - faqs.org

Abstracts

Biological sciences

Search abstracts:
Abstracts » Biological sciences

Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1

Article Abstract:

Transcriptional repression by a Caenorhabditis elegans germ-line protein has been studied. In the early C. elegans embryo, PIE-1 protein, which is maternally expressed, is necessary in germ-line blastomeres to inhibit somatic differentiation, block phosphorylation of the RNA polymerase II large subunit (Pol II) carboxy-terminal domain (CTD) and maintain mRNA transcription absence. It has been found the PIE-1 can act as a transcriptional repressor in cell culture assays. A PIE-1 repression domain that seems to cut back transcriptional machinery directly has been identified. It seems repressor activity may be important for in vivo PIE-1 function.

Author: Dunn, Melanie A., Seydoux, Geraldine, Blackwell, T. Keith, Shim, Eun Yong, Mello, Craig, Batchelder, Ceri, Choy, Bob, Suh, Yong, Cassie, Conrad, Shin, Tae Ho
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 1999
Research, Observations, Caenorhabditis elegans, Zinc in the body, Zinc (Nutrient), Antibody diversity

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA


Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor

Article Abstract:

The author reviews the publications on hypoxia-inducible transcription factors' regulation. The topics include the regulation of this factor by oxygen availability, the physiological role of the hypoxia-inducible transcription factor's prolyl hydroxylases, and the mediation of hypoxia-inducible transcription factor's activity by Fe(II)-dependent dioxygenase enzyme.

Author: Bruick, Richard K.
Publisher: Cold Spring Harbor Laboratory Press
Publication Name: Genes & Development
Subject: Biological sciences
ISSN: 0890-9369
Year: 2003
Oxygen, Industrial Gas Manufacturing, Enzymes, Other Basic Organic Chemical Manufacturing, Industrial gases, Physiological aspects, Hypoxia, Anoxia, Iron compounds, Hydroxylases, Chemical properties

User Contributions:

Comment about this article or add new information about this topic:

CAPTCHA



Subjects list: United States, Genetic aspects, Genetic regulation, Genetic transcription, Transcription (Genetics)
Similar abstracts:
  • Abstracts: Molecular and genetic analysis of unc-7, a Caenorhabditis elegans gene required for coordinated locomotion. Analysis of the Caenorhabditis elegans axonal guidance and outgrowth gene unc-33
  • Abstracts: Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. The mouse homeobox gene Not is required for caudal notochord development and affected by the truncate mutation
  • Abstracts: Isolation and characterization of the canine serotonin receptor 1A gene (htr1A). FISH mapping of two putative keratin gene clusters on cat (Felis catus) chromosomes
  • Abstracts: The genetics of epilepsy in the Belgian turvuren and sheepdog. part 2 Analysis of genetic variation in 28 dog breed populations with 100 microsatellite markers
  • Abstracts: Characterization of microbial communities in gas industry pipelines. Boundaries for biofilm formation: humidity and temperature
This website is not affiliated with document authors or copyright owners. This page is provided for informational purposes only. Unintentional errors are possible.
Some parts © 2025 Advameg, Inc.