orthodenticle Is required for photoreceptor cell development in the Drosophila eye

Article Abstract:

Cellular morphogenesis of Drosophila photoreceptor cells (R cells) during pupation requires the expression of orthodenticle (otd), a homeobox gene. Expression is controlled by a regulatory sequence in the third intron of the otd gene. In this study, it was shown that deletion of this sequence in otd-UV-sensitive, a hypomorphic allele of otd, results in the reduced expressed of otd in the R cells.

Author: Johnson, Denise, Vandendries, Erik R., Reinke, Rosemary
Genetic aspects, Cell differentiation, Photoreceptors

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Drosophila immune response as models for human immunity

Article Abstract:

Insects such as Drosophila melanogaster provide useful models for human immunity. Rel protein signaling cascades have been identified in the immune response of Drosophila. The signaling pathways are markedly similar in Homo and Drosophila. A combination of molecular, genetic, and genomic techniques can be used to study Drosophila immune response.

Author: Dushay, Mitchell S., Eldon, Elizabeth D.
Models, Physiological aspects, Immune response, Human immunogenetics

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The toll immune-regulated drosophila protein fondue is involved in hemolymph clotting and puparium formation

Article Abstract:

A study examines the role of fondue in hemolymph clotting in insects. The activity of antimicrobial peptide is considered in the study.

Author: Lemaitre, Bruno, Scherfer, Christoph, Qazi, Mousumi R., Takahashi, Kuniaki, Ueda, Ryu, Dushay, Mitchell S., Theopold, Ulrich
Sweden, Usage, Observations, Peptides, Control, Fondue, Hemolymph

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Subjects list: Drosophila
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