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Enzyme immobilization in a biomimetic silica support

Article Abstract:

The techniques that are robust immobilized preserves the activity of biomolecules that have many applications such as the harsh conditions required for chemical synthesis, limits the applicability of silicates and others. The use of biosilica for enzyme immobilization combines the excellent support properties of silica matrix with a benign immobilization method that retains enzyme activity.

Analysis, Enzyme activation, Immunoenzyme technique, Immunoenzyme techniques

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US boosts the BSE fight

Article Abstract:

The United States is increasing its efforts to keep bovine spongiform encephalopathy (BSE) out of the country, and will also devote additional funding to research on human variant Creutzfeldt-Jakob disease. The efforts will focus on surveillance, protection, research and oversight. Some specifics of the programs are briefly discussed.

Administration of Public Health Programs, Regulation of Agricultural Marketing and Commodities, Food & Drug Administration, Regulation of agricultural marketing, Admin. of public health programs, Natl Institutes of Health, Health Research Programs, Safety and security measures, Social policy, Medical research, Powers and duties, Bovine spongiform encephalopathy, Creutzfeldt-Jakob disease, United States. Food and Drug Administration, United States. Centers for Disease Control and Prevention

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A new school for screening

Article Abstract:

A fragment-based discovery method, referred as scaffold based drug design is introduced and its utility in the rapid identification of cyclic nucleotide phosphodiesterase (PDE) inhibitors is discussed. The focus is laid on the discovery of novel inhibitors of the PDE enzyme family.

Drugs, Pharmaceutical research

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