Fully mobilizing host defense: building better vaccines

Article Abstract:

Researchers and oncologists have been seeking vaccines and immunotherapies that offer protection against tumors. Vaccines and immunotherapies could be more effective than conventional solutions and show less side-effects. There is an important need to seek protection against numerous pathogenic organisms which cannot be effectively treated by vaccines. The development of effective vaccines depends on the identification methods for cellular antigens that are mainly linked to tumor cells. With infectious diseases, it is important to identify antigens that are connected with the different aspects of infections.

Viral Disease R&D, Viral research

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Selecting and maintaining a diverse T-cell repertoire

Article Abstract:

The immune system looks inward using a variety of self-antigens to choose and maintain a diverse repertoire of receptors in order to provide a T-cell population that will respond quickly to foreign antigen.

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Enhanced major histocompatibility complex class I-dependent presentation of antigens modified with cationic and fusogenic peptides

Article Abstract:

Researchers have created a means of stimulating immunological responses in vivo that has potential use in developing vaccines for antigen-specific immunotherapy for humans.

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