Generation of detectable singlet aryl cations by photodehalogenation of fluoroquinolones
Article Abstract:
Laser flash photolysis (LFP) technique was used to study lomefloxacin (LFX), a carboxylic acid derivative, in an effort to detect putative reaction intermediates in the photodehalogenation process and the reactions were carried out in neutral aqueous solutions both under aerobic and anaerobic conditions. Results showed that a detectable transient species was produced which can be assigned to aryl cation and existence of these species can justify the photogenotoxic properties associated with these antibacterial drugs likely due to direct reaction of their cations with DNA.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
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Photodynamic properties of hypocrellin A, complexes with rare earth trivalent ions: Role of the excited state energies of the metal ions
Article Abstract:
The complexes of hypocrellin A (HA) with rare earth trivalent ions (except [Pm.sup.3+]) are synthesized along with the complex of HA with [Sc.sup.3+] and their photodynamic activities are compared by using the UV-visible spectrum, fluorescence spectrum, spin-trapping EPR method and laser photolysis method. The photodynamic activity of the paramagnetic ion complexes of HA is reduced, which is discussed in terms of the excited-state levels of the metal ions.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
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Laser control of desorption through selective surface excitation
Article Abstract:
The mechanisms of laser control of photodesorption from alkali halides using frequency selected laser pulses are discussed. The results demonstrate that laser desorption can serve as a solid-state source of halogen and oxygen atoms, in well-defined electronic and velocity states, for studying chemical processes in the gas phase and at surfaces.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2005
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