Investigation of the influence of spacer arm on the structural evolution of affinity ligands supported on agarose
Article Abstract:
A computational examination of the nature of the interaction between the affinity ligand and the agarose support to which it was bound through spacers of varying length and chemical nature is done through molecular dynamics. It is demonstrated that a change in the spacer properties could decide a change of the stable structure of the ligand with respect to the support and that if a support is not held fixed through restraints, the interaction forces between vicinal ligands will determine a major conformational change of the system.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2006
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Conformational analysis of the electron-transfer kinetics across oligoproline peptides using N,N-Dimethyl-1,4-benzenediamine donors and pyrene-1-sulfonyl acceptors
Article Abstract:
A fluorescence quenching techniques were applied in the conformational analysis of photoinduced intramolecular charge separation across proline-bridged donor-acceptor complexes of the type Pyr-[(Pro).sub.n]-DMPD where Pyr stands for pyrene-1-sulfonyl and DMPD for N,N-dimethyl-1,4-phenylenediamine). It is observed that the Pyr-[(Pro).sub.n]-DMPD molecule with n=2 forms and exciplex, specifically at higher concentrations while the n=3 molecules form exciplexes at a lesser extent.
Publication Name: Journal of Physical Chemistry B
Subject: Chemicals, plastics and rubber industries
ISSN: 1520-6106
Year: 2007
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