Carbene-alkyne-alkene cyclization reactions
Article Abstract:
Transition-metal-based reactions are frequently used chemical reactions in organic synthesis. The efficiency of these reactions lie on their ability to exhibit high levels of chemo-, regio-, and stereoselectivity despite having high reactivity. They also create several new bonds in a single operation. This review focuses on the reactions of a variety of transition metal carbene complexes with alkynes and alkenes via cyclizations for the construction of vinylcarbene complex and metallacyclobutane intermediates, respectively. The discussion includes the factors influencing carbene-alkyne-alkene cyclization reactions.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1996
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Cyclic carbopalladation. A versatile synthetic methodology for the construction of cyclic organic compounds
Article Abstract:
Palladium (Pd) complexes are finding wide applicability in organic synthesis as reaction catalysts because they allow easy entry of carbon-carbon bonds and exhibit reversible interconversion between two stable oxidation states. This versatility has prodded chemists to explore the possibility of using Pd complexes in cyclization reactions. This review focuses on a new synthetic methodology for the creation of cyclic organic compounds via cyclic carbopalladation. The discussion includes examples of reactions involving carbopalladation with alkenes, alkynes, conjugated dienes and allenes.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1996
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