Kinetics and mechanisms for the cleavage and isomerization of the phosphodiester bonds of RNA by Bronsted acids and bases
Article Abstract:
A study was conducted to examine quantitative information on cleavage and isomerization of RNA phosphodiester bonds by Bronsted acids and bases. The pH-rate profiles for the transesterifications were determined over a wide range of acidity while an analogous stepwise mechanism was utilized for the hydronium ion catalyzed cyclization of phosphodiester. The kinetic term associated with the dependence of rate on (SH2) predominated with the isomerization and cleavage over a narrow acidity range around pH 3.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1998
User Contributions:
Comment about this article or add new information about this topic:
Unimolecular photochemistry of anthracenes
Article Abstract:
The electron spectral properties, photolytic transformations, intramolecular energy transfer and excited-state reactions of anthracenes in various forms are discussed. Unimolecular photochemical reactions of anthracene extracts, bichromophoric anthracene intramolecular reactions in particular, are also reviewed. Anthracene pi-system prevails as the most useful method for studying photochemistry of micelles and DNA energy transfer.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
Photochemical one-way adiabatic isomerization of aromatic olefins
Article Abstract:
The photoisomerization around the double bond and one-way internal rotation around the single bond in an excited single state are discussed. The two-way isomerization between cis and trans isomers changes to a one-way isomerization at an adiabatic rate through quantum chain process. Molecular structural factors causing one-way isomerization are viewed with regards to mechanism, potential energy topology and quantum chain process.
Publication Name: Chemical Reviews
Subject: Chemistry
ISSN: 0009-2665
Year: 1993
User Contributions:
Comment about this article or add new information about this topic:
- Abstracts: Protein radicals in enzyme catalysis. Mechanism of free radical oxygenation of polyunsaturated fatty acids by cyclooxygenases
- Abstracts: Chiral titanium complexes for enantioselective addition of nucleophiles to carbonyl groups. The chemistry of thietane ligands in polynuclear metal carbonyl complexes
- Abstracts: Peptides and proteins in the vapor phase. Experiments on the dynamics of molecular processes: a chronicle of fifty years
- Abstracts: The chemistry of gibberellins: an overview. Recent developments in mass spectrometry for the characterization of nucleosides, nucleotides, oligonucleotides, and nucleic acids
- Abstracts: Synthesis and diastereoselective reactions of N,N-dibenzylamino aldehydes and related compounds. Substrate-directable chemical reactions